Hi lhutchings,
If you have an existing opening with a lintel and you are removing the brickwork below then it should be structurally safe. If you are making a new opening or widening an existing opening then you will need to make a submission to building control who will be able to give you general advise on what is required. If you are intending to use a "Catnic" lintel these are generally already pre-approved for building reg's. If not you might need to get structural calculations.
Hope that helps.
Thanks
Stuart